Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment

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Improved radiation dose efficiency in solution SAXS using a sheath flow sample environment

Radiation damage is a major limitation to synchrotron small-angle X-ray scattering analysis of biomacromolecules. Flowing the sample during exposure helps to reduce the problem, but its effectiveness in the laminar-flow regime is limited by slow flow velocity at the walls of sample cells. To overcome this limitation, the coflow method was developed, where the sample flows through the centre of ...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section D Structural Biology

سال: 2016

ISSN: 2059-7983

DOI: 10.1107/s2059798316017174